Microbial Gene Expression (EGM)
From RNA biogenesis to translation and decay, deciphering microbial gene expression
Unit Director: Carine Tisné
CNRS – UMR8261 ⎥Université Paris Cité ⎥Institut de Biologie Physico-Chimique
5
Research Teams
∼ 60+
Years of research
40+ Publications
in the last 5 years
4
model organisms
Our research teams
RNA MAturation and Decay
Team Leader
CIARAN CONDON
Identification, characterization and regulation of ribonucleases in Bacillus subtilis.
Biogenesis architecture and interaction of RNA
Team Leader
CARINE TISNE
Structural and molecular mechanisms of RNA maturation, modification and processing.
RNA control of gene expression
Team Leader
MAUDE GUILLIER
RNA-mediated regulation of bacterial gene expression and regulatory networks.
Physiology and regulation of protein synthesis
Team Leader
GREGORY BOEL
Molecular mechanisms and physiological regulation of bacterial protein synthesis.
Epitranscriptomic and translational responses to anti-bacterial stress
Team Leader
ZEYNEP BAHAROGLU
RNA modifications and translational responses underlying bacterial stress adaptation and antibiotic tolerance.
LATEST NEWS
Oct 20, 2026
Oct 1, 2026
Sept 21, 2026
Sept 16, 2026
As every year, our unit will welcome 13 students from the M1 BMC Immersion module at Université Paris Cité during the week of 23 November, giving them the opportunity to discover the research activities carried out at the IBPC.
UPCOMING SEMINARS
NOV.
02
Lionel BENARD
(IBPC)
“Les voies de surveillance des ARNs”
11:00 – Bibliothèque
NOV.
03
Albertas NAVICKAS
(Institut Curie)
“ARN et progression tumorale”
11:00 – Bibliothèque
NOV.
04
Anastasia KOMAROVA
(Institut Pasteur)
“Virus et ARN”
11:00 – Bibliothèque
NOV.
05
Zeynep BAHAROGLU
(IBPC)
“Modification des ARNt et tolérance aux antibiotiques chez Vibrio”
11:00 – Bibliothèque
NOV.
06
Etienne DELANNOY
(IPS2)
“RNA editing in plants”
11:00 – Bibliothèque
SELECTED PUBLICATIONS
Mathis de Fromont J, Brosse A, Quenette F, Guillier M. SamT, a novel peptide modulator of a two-component system revealed by the specific activation of a small RNA in Enterobacteriaceae. Nucleic Acids Research, 2026. DOI: 10.1093/nar/gkag727..
Yared M-J, Chagneau C, Barraud P. Mapping the temporality and structural impacts of modifications in Escherichia coli tRNAs. Journal of Biological Chemistry, 2026, 302(4):111337. DOI: 10.1016/j.jbc.2026.111337.
Monlezun L, Earl C, Coulthurst SJ. Tvp complexes support formation of the VgrG-PAAR spike during Type VI secretion system assembly. EMBO Journal, 2026. DOI: 10.1038/s44318-026-00820-1.